Harry Kane and Dele Alli could make their Tottenham return against Saints in March.
The duo's injuries have denten ex-Saint Mauricio Pochettino’s side in their quest for a Champions League spot.
Kane suffered ligament damage to his ankle in Spurs’ 1-0 defeat to Manchester United at Wembley Stadium earlier this month.
Tottenham's Harry Kane limps off during the defeat to Manchester United
Alli joined his teammate in the treatment room following the 2-1 victory over Saints’ relegation rivals Fulham on Sunday.
The midfielder’s scan showed that he’s pulled his hamstring, which will keep him out of action until March.
Spurs are due to play Saints at St Mary's on Saturday, 9 March.
Dele Alli receives treatment during the Fulham match
Before his injury, Kane was battling Liverpool's Mo Salah to win this year's race for the Golden Boot.
Kane has netted 14 times, compared to Salah's 16.
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